The Mercedes driver's 55th career win was hard-fought and tense, however, with Ferrari's Vettel seizing the lead at the start and in the hunt all the way to the finish as the tyre strategies played out.
Mercedes' Lewis Hamilton showed his mastery in the wet to chalk up his third pole position in four races in Chinese Grand Prix qualifying on Saturday.
Lewis Hamilton drove a superb tactical race to hold off his McLaren team-mate Jenson Button and win Sunday's Canadian Grand Prix from pole position and jump to the top of the Formula One drivers' championship.
Rookie sensation Lewis Hamilton can stretch his championship lead and add to the discomfort of McLaren team mate Fernando Alonso in Sunday's US Grand Prix.
The Briton said McLaren are giving him the same chance of winning the title this season as team mate Fernando Alonso.
McLaren's Lewis Hamilton took pole position for the season-opening Australian Grand Prix on Saturday ahead of teammate Jenson Button as world champion Sebastian Vettel was banished to the third row of the grid.
McLaren's Lewis Hamilton said on Wednesday he could still win next week's French Grand Prix despite a 10-place penalty on the starting grid. Hamilton picked up the penalty after piling into the rear of Formula One world champion Kimi Raikkonen's Ferrari in the Canadian Grand Prix pit-lane last Sunday.
Mercedes can hardly wait for Sunday's Abu Dhabi Formula One title decider to be over so they can tie Lewis Hamilton down to a long-term contract.
Six-times world champion Lewis Hamilton dominated the Styrian Grand Prix in a Mercedes one-two on Sunday to celebrate his 85th Formula One win and move a step closer to Michael Schumacher's record of 91 victories. Finnish Team mate Valtteri Bottas, winner of last weekend's season-opener behind closed doors at the same Austrian circuit, finished a distant runner-up with his championship lead cut to six points.
No one was happier to see Formula One back in America on Sunday than McLaren's Lewis Hamilton as the Briton picked up where he left off in 2007 by winning the United States Grand Prix.
The 22-year-old Briton was unimpressed after being forced off the track by Fernando Alonso at the start of the Belgian Grand Prix.
Lewis Hamilton won in Sunday's Azerbaijan Grand Prix ahead of Kimi Raikkonen and took championship lead.
Nico Rosberg secured pole position for the Russian Grand Prix after Mercedes team mate Lewis Hamilton suffered more misfortune in Saturday's qualifying.
Lewis Hamilton's hopes of clinching his fifth Formula One World championship at the US Grand Prix were boosted on Friday when Ferrari rival Sebastian Vettel was handed a three-place grid penalty for a practice infringement.
Lewis Hamilton may have had some regrets already about his decision to join Mercedes next season, according to his McLaren Formula One team principal Martin Whitmarsh.
Lewis Hamilton was fined 6,869 pounds ($10,000) and reprimanded for failing to return his car to the pits quickly enough after claiming pole position during qualifying for the Canadian Grand Prix Saturday.
'Tolerance is an elementary principle of our team and we are enriched by diversity in all its forms.'
Lewis Hamilton believes his Mercedes Formula One team can live up to their advance billing as favourites when the season starts in Australia next week.
The Mercedes driver told reporters he would seek a clarification from race director Charlie Whiting ahead of the next race in Spain.
Fernando Alonso hailed the Briton as a Formula One great and said he was happy to see him stand on the brink of a fifth world championship.
Formula One world champion Lewis Hamilton took pole position for the season-opening Australian Grand Prix on Saturday ahead of Mercedes team mate Nico Rosberg as the Silver Arrows continued to underline their dominance.
Lewis Hamilton grabbed McLaren's 150th Formula One pole on Saturday in a Spanish Grand Prix qualifying that left him well-placed to become the fifth different winner in five races.
Six time world champion Lewis Hamilton, winner of the British Grand Prix from pole position at the same circuit last weekend and 30 points clear of Valtteri Bottas after four races without spectators, was 0.138 seconds slower.
Mercedes's Valtteri Bottas snatched pole position for the US Grand Prix on Saturday, breathing life into his remote title hopes while signalling to Lewis Hamilton he will not be gifting a sixth drivers' crown to his team mate.
Lewis Hamilton enjoyed an utterly dominant Italian Grand Prix victory on Sunday to take a 53-point lead in the Formula One championship after Mercedes team mate and closest rival Nico Rosberg retired with his engine in flames.
Lewis Hamilton can become only the third driver to win 50 grands prix when Formula One returns from its month-long August break and gets back to business at Sunday's Belgian Grand Prix.
Lewis Hamilton is hoping rain will come to the rescue as a Hockenheim heatwave threatens to dash Mercedes's hopes of a home German Grand Prix win on Sunday.
Formula One world champion Lewis Hamilton took pole position for his home British Grand Prix on Saturday with Mercedes teammate and title rival Nico Rosberg qualifying alongside on the front row.
Formula One world champion Lewis Hamilton revived memories of last year's glories Thursday with his most competitive showing yet this season in Monaco Grand Prix practice. The 24-year-old Briton, who won in Monaco last year but has struggled with an under-performing McLaren in the first five races of 2009, was third fastest in the morning session and second in the afternoon.
'It's a great job by the team. Usually in the first day you don't get that many laps so I'm really happy'
The Briton's fourth victory in five races suggests that once again the 33-year-old is hitting a purple phase just as the season enters its critical stages.
Sudden tyre failure wrecked Lewis Hamilton's hopes of a home British Grand Prix victory on Sunday after the Mercedes driver had led from pole position.
Nico Rosberg won the Brazilian Formula One Grand Prix for the second year in a row on Sunday and denied Mercedes teammate Lewis Hamilton a first success in the homeland of his late hero Ayrton Senna.
Lewis Hamilton refused to take questions from the media after qualifying second for Sunday's Japanese Grand Prix due to "disrespectful" criticism of his behaviour during a news conference two days ago.
Mercedes driver Lewis Hamilton will start the Chinese Formula One Grand Prix from pole position after setting the fastest time in qualifying on Saturday.
Lewis Hamilton stormed to pole position at the Brazilian Grand Prix on Saturday with Mercedes team mate and title rival Nico Rosberg joining the triple Formula One world champion on the front row. On a damp and overcast Sao Paulo afternoon, it was the 60th pole of the Briton's career, eight short of Michael Schumacher's record, and his first in Brazil since 2012 when he was at McLaren. With his title on the line, it was also one of Hamilton's most important in a roller-coaster season marked by mechanical setbacks.
The Briton made the comments in an interview to the BBC in reference to Formula 1 embracing new countries to hold races.
Hamilton already had more race wins, pole positions and podium finishes than any other driver in the history of the sport.
Fresh from his 50th Formula One win, triple world champion Lewis Hamilton remains convinced anything is possible in the title race even if he could lose his crown as early as Sunday.
McLaren's Lewis Hamilton was stripped of victory in a thrilling Belgian Grand Prix after stewards decided he had gained an advantage by cutting a chicane during a last-gasp duel with Kimi Raikkonen.